Seachem Prime is the complete and concentrated conditioner for both fresh and saltwater. Seachem Prime removes chlorine, chloramine and detoxifies ammonia, nitrite, and nitrate. It is non-acidic and will not impact pH. Seachem Prime may be used during tank cycling to alleviate ammonia/nitrite toxicity. It contains a binder that renders ammonia, nitrite, and nitrate non-toxic, allowing the biofilter to more efficiently remove them. It will also detoxify any heavy metals found in the tap water at typical concentration levels. Use at start-up and whenever adding or replacing water.